Science and Technology Grand View: The Enlightenment of Medical Innovation Brought by "Artificial Skin"

The skin is the largest organ in the human body. However, some accidents, illnesses, and even human mental states can change the appearance and function of the skin. How to restore the ideal skin condition has always been a problem. Recently, researchers at Harvard University-Massachusetts Institute of Health Sciences and Technology (HST) have developed an "artificial skin" that mimics the characteristics of healthy young skin and is expected to become the "second skin" of humans.

The study found that when a silicone-based polymer material is applied to human skin, it can be cross-linked in situ to form a thin layer of three-dimensional network structure, which has similar appearance, elasticity, strength and health to healthy skin. Moisturizing effect. If this material is applied under the eyes, the skin can be immediately tightened, effectively eliminating eye bags. In addition, this layer of "skin" can effectively conceal some scars such as port wine stains, thereby reducing the psychological stress of patients. More importantly, various sustained-release drugs can be added to the "skin" to treat skin diseases. Because the polymer material is safe and non-irritating to the skin, it is convenient to apply and can be made into various dosage forms such as eye cream and spray.

For many years, dermatologists have been hoping to develop simulated skin to solve the clinical problems of various skin diseases, and the various materials of this past life can not perfectly simulate the skin characteristics. This elastic, moisturizing "artificial skin" not only adds to the beauty of the people, but also brings good news to patients such as burns. In the future, patients who need skin grafts can no longer “remove the east wall to make up the Western Wall”, transplant with their own skin and thus leave more scars; and avoid waiting for donors and subsequent rejection reactions.

"Artificial skin" crosses many disciplines such as medicine, biology, chemistry, materials, engineering, etc. Through continuous screening, optimization and clinical testing of materials, this result is finally achieved. This is also the charm of the “source-based innovation” model in the medical field. In reality, there are many similar results, such as the close collaboration between cardiac surgeons and electrical engineers and computer scientists, using 3D printing to transform the scanned image of a patient's diseased heart into a physical model for cardiac surgery.

Harvard University—The Department of Health Sciences and Technology at the Massachusetts Institute of Technology is the oldest and largest training platform for physician scientists in the United States. Any creative ideas that clinicians make based on actual work can use this platform to find solutions that ultimately translate into results. Students at Harvard Medical School can also join the platform and build themselves into a doctor with “cross-border” innovation.

Historically, any medical technology and medical device innovation was not done by a clinician or a subject expert alone. Multidisciplinary cross-disciplinary cooperation based on clinical issues can truly achieve independent innovation in medical technology and medical devices. This efficient and new model is an inspiration for the research and medical sectors of all countries. Recently, the Chinese Cardiovascular Doctor Innovation Club initiated by the Chinese Academy of Sciences Ge Gebo, the participants of cross-border discussion at multiple levels and in many fields, is an attempt of this kind of cross-integration “source innovation” in China.

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