In a strict sense, this scene has not yet fully become a reality, but it is not far off. In addition to the soluble circuits, on September 17, 2014, scientists published the latest results on degradable wireless control tank circuits at Advanced Materials, and have already tested them in mice.
This finding can be said to be a very important step in the bio-electronics field to expand into medicines – micro-devices dissolve automatically after completing treatment tasks. Such techniques will be applied to include the stimulation of nerve and bone growth, in combination with wound healing, drug delivery, and antibiotics.
John Rogers, a mechanical engineer at the University of Illinois, said: "In applications, these small devices only need to work at some point in the treatment process. After that, the ideal state is that they can degradation."
Last year John published a study on circuits for water-soluble silicon materials; this year, he and his team developed miniature LEDs that can be implanted into the brain.
This wireless control circuit is attached to an ultra-thin silk substrate and responds to different frequency signals. John's team made capacitive, inductive, and resistive components using water-soluble biomaterials: nano-silicon films as semiconductors; magnesium, which is an important component of the organism itself; silica or magnesia, as an insulating part; and ultra-thin silk As a substrate for the device.
The very important antenna in the entire wireless control circuit - used to receive wireless signals and converted into electrical energy to drive the circuit - is made of magnesium laid on the surface of the silk. A 500-nanometer ultra-fine magnesium antenna can be completely dissolved in deionized water at room temperature in just 2 hours; and an antenna 6 times larger than this can take only a few days.
To prove the operation of the circuit, John and his colleagues connected the magnesium antenna to the LED to build an energy-receiving circuit. Then they turned on a wireless transmitter 6 feet away, and the circuit could convert 15% of the energy into Power, and led starts to flash. Finally, they placed the circuit in deionized water and the circuit dissolved smoothly.
In this regard, Christopher Bettinger of Carnegie Mellon University said that this is important for the development of biodegradable electronic systems. At the same time, he also pointed out that the use of radio waves as an energy source means that the deeper the device is implanted, the larger the antenna size required. “I think the supply of energy will be a real problem for biodegradable electronics,†he said. “This definitely brings a very important application, but we also need to clearly define which diseases we have in the field of treatment than traditional treatments. The advantages."
Currently, John and his colleagues are testing a hyperthermia instrument on mice. Through the infrared camera, they can see if the equipment implanted under the skin is working properly; when they work, the skin around them will rise slightly by a few degrees Celsius. They said that there is currently no inflammation, fibrotic lesions or other side effects during implantation and reabsorption of the device.
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