New progress in human transplantation 3D printing medical technology
Over time, bio 3D printing technology has made some good progress. But it is still decades away from the real transplantation of biological 3D printing organs and tissues. At the same time, scientists have re-applied the technology to 3D printed biocompatible high-precision silicone implants.
However, soft materials such as biomaterials or silicones are difficult to perform 3D printing because they cannot support themselves like the rigid materials commonly used in 3D printers. In 2015, the University of Florida's Tommy Angelini Lab developed a new 3D printed soft material that was injected into a granular gel similar to a disinfectant to support them during printing.
This allows them to print a variety of shapes using hydrogels, silicones and other polymers, including organ reproduction that allows the surgeon to perform surgery prior to surgery. They also managed to use this method to print live cells, which suggests it is useful for bio 3D printing.
Although significant progress has been made in bioprinting in recent years, actual medical use has been for decades. Technology analyst IDTechEx predicts that by 2027, the value of the global bio 3D printing market will reach $1.8 billion, but this growth will depend on applications such as drug screening and the development of cosmetics and other consumer products.
In contrast, silica gel has been widely used in medical implants, including catheters for draining body fluids, pacemakers, and stents designed for airways. 3D printing of these devices enables highly customized implants to be produced at lower cost and faster.
However, two years ago, Angelini and colleagues designed a method to achieve 3D printing on silica gel with limited accuracy and strength. This is due to the fact that the particulate gel material is aqueous and incompatible with oily silicone inks.
The group has now created a new oil-based gel that enables ultra-high precision 3D printed silicone construction with high durability. This allows them to create 3D stents, hollow vessel networks, functional fluid pumps, and even model tracheal implants.
Angelini said in the press release: "In fact, it may take us decades to fully implant 3D printed tissues and organs into patients. By contrast, inanimate medical devices have been widely used for implantation. We developed ahead of other bio 3D printing technologies, and silicone devices can be used extensively without the technical limited delay."
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