The world's first bioengineered cornea China listed 196 million big orders

Release date: 2015-12-07

China Regenerative Medicine announced on December 1 that it has reached a strategic agreement with well-known pharmaceutical companies including China Instruments, State Control Shaanxi, Guangdong Sanxin, Tianjin Bio, Zhejiang Eisai, Jiangsu Huaihai, and officially sold the world's first R&D and production nationwide. A bioengineered cornea "Ai Xinyi". "First Financial Daily" learned from Chinese regenerative medicine that the agreement requires that as of December 31, 2018, 22 agents would develop 108 hospitals in 22 provinces or municipalities in China to sell "Ai Xinyi" - as of On December 31, 2016, the total contract value of the cooperation agreement was approximately RMB 196 million.

According to public information, China is one of the most blind countries in the world. According to the World Health Organization's 2010 Global Data Report on Visual Disability, there are 8.248 million blind people in China, accounting for 18% of the world's total blind population. It has already exceeded the population of countries such as Denmark, Finland and Norway. Among them, corneal disease is one of the most important blind eye diseases. It is the second most common blind eye disease after cataract in developing countries and the first factor for eyeball removal. In 2006, the second national statistical survey of disabled persons survey showed that about 4 million people were blinded by corneal diseases, 85% of corneal blindness was caused by infectious keratopathy, and about 100,000 new corneal blind patients were born each year. .

At the same time, however, due to the constraints of traditional concepts, China's corneal donors are seriously deficient. The country's annual corneal donation is only 3,000 cases, and the donation rate is less than one tenth of that in the United States. Many patients are blind because they cannot perform corneal transplantation in time. Some even forced to remove the eyeball and forever lose hope of recovery.
Zou Liuhe, professor of ophthalmology at Beijing Tongren Hospital, believes that the most important feature of bioengineered cornea is its good fusion. The acellular corneal stroma is naturally integrated with the human eye. At present, some artificial corneal products in foreign countries mainly use silica gel as the material, and the patient's rejection reaction is obvious.

Dr. Shao Zhengkang, CEO of China Regenerative Medicine International Co., Ltd. told this reporter that the future development of Chinese regenerative medicine will be based on bioengineered corneal and tissue engineering skin-oriented tissue engineering product development, cell and stem cell research and development and clinical applications, cosmetics and Research and development of anti-aging products and research and development, production and sales of high-end medical device products.

In 2014, China's Regenerative Medicine and Oxford University established the first China R&D University of Oxford Technology R&D Center, and provided the center with a total of 7.5 million pounds to fund a therapeutic research project for major blind spots in clinical applications. However, it is not limited to the use of stem cells for the treatment of diabetes, cancer, neurodegenerative diseases, and organ repair.

In 2015, China Regenerative Medicine spent about HK$200 million in the Hong Kong Science Park to build the world's highest GMP specifications, in line with European, American and Chinese clinical stem cell research and application centers. The application center will provide the most efficient production conditions for the storage, separation, amplification, induction and differentiation of stem cells in cell therapy, and is expected to be operational by the end of 2016.

Source: Yicai.com

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