Release date: 2016-04-13
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-- Recently, in a research report published in the journal Liver Transplantation , researchers from abroad analyzed the epidemiological characteristics and risk factors of fatty liver disease in liver transplant patients. The related research is to develop new strategies to protect organ transplant patients. The health may provide some research clues.
Steatosis, in which the liver is infiltrated by fat, usually occurs in liver transplant patients, but current researchers are not aware of the actual epidemiological characteristics of fatty liver in liver transplant patients, and it is not clear about the relevant risk factors and How to improve the survival rate of liver transplant patients. To this end, the researchers conducted a retrospective analysis and study of liver biopsy and survival data from 548 liver transplant patients.
The researchers found 309 patients with fatty liver (56.4%), including 93 (17.0%) patients with significant fatty liver. The researchers pointed out that the prevalence of fatty liver in patients after liver transplantation was 1 year. 30.3% of the time increased to 47.6% after 10 years; when the researchers analyzed the characteristics of the patients before transplantation, they found that the higher body mass index and cirrhosis caused by drinking often existed between patients and fatty liver. Significantly related, by analyzing the patient's performance after transplantation of the liver, the researchers found that higher body mass index, hyperlipidemia, alcohol consumption and type 2 diabetes have a certain association with fatty liver in patients; this indicates that patients after liver transplantation within a few years There is no association between fatty liver and poor survival in patients, but the long-term survival rate of patients with severe fatty liver may become more severe.
The final researcher, Hejlova, said that our study was the first to study a large number of European liver transplant patients, describing the occurrence, progression and other characteristics of fatty liver in these patients; the occurrence of fatty liver suggests that the long-term survival rate of these patients may be affected, Obesity can be avoided in these patients, and patients should be encouraged to increase physical activity to improve disease progression; researchers suggest screening and treatment for diabetes and hyperlipidemia, and restricting alcohol consumption to effectively improve fatty liver in liver transplant patients. The progress of the disease and the survival rate of the patient may provide some help.
Source: Bio Valley
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