Hypertension has a risk of mild cognitive impairment in the elderly
January 30, 2019 Source: Science and Technology Daily Author: Liu Haiying
Window._bd_share_config={ "common":{ "bdSnsKey":{ },"bdText":"","bdMini":"2","bdMiniList":false,"bdPic":"","bdStyle":" 0","bdSize":"16"},"share":{ }};with(document)0[(getElementsByTagName('head')[0]||body).appendChild(createElement('script')) .src='http://bdimg.share.baidu.com/static/api/js/share.js?v=89860593.js?cdnversion='+~(-new Date()/36e5)];Alzheimer's disease is expected to affect 115 million people worldwide by 2050, but there are no treatments that have been shown to reduce the risk of dementia. A new study in the United States shows that hypertension is a precursor to dementia, a potential risk factor for mild cognitive impairment. Although lowering blood pressure does not significantly reduce the risk of dementia, it can have a measurable effect on mild cognitive impairment. Related research was published in the Journal of the American Medical Association on the 28th.
The study was funded by the National Institutes of Health to assess the impact of enhanced blood pressure control on the risk of dementia. During the study, approximately 9,400 hypertensive patients over the age of 50 were randomized into two groups, receiving intensive blood pressure therapy (with systolic blood pressure below 120 mm Hg) and standard treatment (with systolic blood pressure control). Below 140 mm Hg). The researchers then followed up on these patients and found no statistically significant difference between standard and intensive treatment in the proportion of patients diagnosed with dementia. This suggests that intensive blood pressure control did not result in a significant reduction in the risk of dementia compared to standard treatment. But the study also showed that intensive treatment reduced the risk of participants with mild cognitive impairment.
Richard Holtz, director of the National Institute on Aging (NIA), pointed out that dementia is a huge challenge in the global public health field. Although the new research did not help find an intervention strategy that can reduce the risk of dementia, it shows that Intensive lowering of blood pressure may reduce the risk of mild cognitive impairment, which provides scientists with more ways to explore dementia prevention. Dr. Leno Launer, a senior NIA researcher, said that the study was a milestone as the first attempt by scientists to study the risk factors for dementia and mild cognitive impairment.
The author of the paper, Jeff Williamson of Wake Forest University School of Medicine, stressed that although clinical trials have demonstrated that interventions can significantly reduce the incidence of mild cognitive impairment, mild cognitive impairment is not the primary focus of the study. At the same time, the significance of strengthening blood pressure control on the incidence of long-term dementia is still unclear, so it should be cautious in interpreting the relevant research results.
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