Gecko tails can be reborn, broken shark teeth will grow up, why humans only have deciduous teeth and permanent teeth in their lifetime, teeth can not be regenerated? This problem has been plagued by researchers all over the world. Recently, Professor Jin Yan and his research team of the Tissue Engineering Center of the Stomatological Hospital of the Air Force Military Medical University have successfully achieved dental pulp regeneration after 20 years of efforts, making the treatment of oral diseases a new milestone.
The realization of pulp regeneration has always been a world problem. The research team led by Jinyan established a cell aggregate technology based on stem cell self-assembly by simulating the principle of tooth development, and successfully realized the functional regeneration of whole pulp tissue by using the deciduous deciduous stem cells, and carried out the international first full-length pulp regeneration. Research and success.
For many years, dental pulp disease has been treated with “root canal therapy†in clinical treatment, which is to completely remove the dental pulp cells in the pulp and root canals of the teeth and fill them with biological materials. Although the teeth are retained after filling, they gradually become brittle and discolored, and they also lose their feeling. The pulp regeneration technique is to obtain dental pulp stem cells from the patient's deciduous deciduous teeth. After one month or so of in vitro culture, the formed stem cell polymer is implanted into the pulp cavity required by the patient, so that the nerve regeneration of the teeth is completed, and the tooth original is completely restored. Has a function. Especially for young patients whose teeth are developing, the teeth can develop to a normal state.
It is reported that the technology has been used in nearly 50 clinical patients, and all of them have been completely successful. The results were published in the journal Science Translational Medicine in the United States, which attracted widespread international attention. The successful development of this technology has changed the traditional concept of dental treatment and is of great significance in the field of dental regeneration.
People's Daily (12th edition, August 31, 2018)
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