1. Quick Detail:
Â
Synonyms: 11-(4-(dimethylamino)phenyl)-17-hydroxy-17-(1-propynyl)-estra-9-dien-3-one;11beta-[4-(n,n-dimethylamino)phenyl]-17alpha-(prop-1-ynyl)-delta4,9-estradiene;17-beta)-(11-bet;17beta)-11-[4-(dimethylamino)-phenyl]-17-hydroxy-17-(1-propynyl)estra-(11bet;17-beta-hydroxy-11-beta-(4-dimethylaminophenyl-1)-17-alpha-(prop-1-ynyl)oest;-17beta-ol-3-one;4,9-dien-3-one;r38486Â
Mifepristone Mifepristone
Mifepristone CAS No.: 84371-65-3
Mifepristone Molecular Formula: C29H35NO2
Mifepristone Molecular Weight: 429.65
Mifepristone Melting Point: 195-198 Degree C
Mifepristone Description: White or almost white or pale yellow crystalline powder
Mifepristone Packing: 1kg/aluminum foil bag
Mifepristone 2. Min. Order quantity: 5g
Mifepristone 3. Payment: Western Union, Moneygram
Mifepristone 4. Shipment: EMS, DHL, FedEx
Mifepristone 5. Delivery: Safe & timely, around 7days after payment.
2. Description:
Mifepristone is a synthetic steroid compound with both antiprogesterone and antiglucocorticoid properties. The compound is a 19-nor steroid with substitutions at positions C11 and C17 (17 beta-hydroxy-11 beta-[4-dimethylamino phenyl] 17 alpha-[1-propynyl]estra-4, 9-dien-3-one), which antagonizes cortisol action competitively at the receptor level.Â
Mifepristone is a progesterone receptor antagonist used as an abortifacient in the first months of pregnancy, and in smaller doses as an emergency contraceptive. It is also a powerful glucocorticoid receptor antagonist,Â
Mifepristone was the first antiprogestin to be developed and it has been evaluated extensively for its use as an abortifacient. The original target for the research group, however, was the discovery and development of compounds with antiglucocorticoid properties. These antiglucocorticoid properties are of great interest in the treatment of severe mood disorders and psychosis, although a review of published articles was inconclusive on their efficacy, and considered the use of these drugs in mood disorders at 'proof of concept' stage. It is on the World Health Organization's List of Essential Medicines.Â
3.Application:
Mifepristone is used alone or in combination with misoprostol (Cytotec) to end an early pregnancy. Early pregnancy means it has been 49 days or less since your last menstrual period began. Mifepristone is in a class of medications called antiprogestational steroids. It works by blocking the activity of progesterone, a substance your body makes to help continue pregnancy.
Mifepristone is also available as another product (Korlym), which is used to control hyperglycemia (high blood sugar) in people with a certain type of Cushing's Syndrome in which the body makes too much of the hormone cortisol. This monograph only gives information about mifepristone (Mifeprex), which is used alone or in combination with another medication to end an early pregnancy. If you are using mifepristone to control hyperglycemia caused by Cushing's syndrome, read the monograph entitled mifepristone (Korlym) that has been written about this product.
Mifepristone COA
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Ref. Standard |
According to the CP 2010 version and enterprise internal control standard inspection | ||
Results Of Analysis Tests | |||
Test | Analysis StandardResults |  | |
Description | Light Yellowish Crystalline Powder |  Light Yellowish Crystalline Powder | |
Identification | (1)304nm,260nm. | confirmed | |
Melting Point | 192ºC~196ºC | 192ºC~196ºC | |
Specific Rotation | +124°~ +129° | +127.1° | |
(HPLC) Related substances | (1)(Single):≤0.5% | 0.31% | |
 | (2)(Total):≤1.0% | 0.59% | |
Loss On Drying | ≤0.5% | 0.1% | |
Assay | ≥98.5% | 99.5% | |
Sieve analysis | ≤30¦Ìm | confirmed | |
Conclusion | This product conforms to the CP 2010 and enterprise internal control standards |
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Name |
Specification |
MGF | 2mg/vial |
PEG MGF | 2mg/vial |
CJC-1295 with DAC | 2mg/vial |
CJC-1295 without DAC | 2mg/vial |
PT-141 | 10mg/vial |
MT-1(Melanotan) | 10mg/vial |
MT-2 | 10mg/vial |
GHRP-2 | 5mg/vial |
GHRP-2 | 10mg/vial |
GHRP-6 | 5mg/vial |
GHRP-6 | 10mg/vial |
Ipamorelin | 2mg/vial |
Hexarelin | 2mg/vial |
Sermorelin | 2mg/vial |
Oxytocin | 2mg/vial |
TB500 | 2mg/vial |
pentadecapeptide BPC 157 | 2mg/vial |
176-191 | 2mg/vial |
Triptorelin | 2mg/vial |
Tesamorelin | 2mg/vial |
Gonadorelin | 2mg/vial |
Gonadorelin | 10mg/vial |
DSIP | 2mg/vial |
Selank | 5mg/vial |
CAS:94-24-6 | Tetracaine base |
CAS:136-47-0 | Tetracaine hydrochloride |
CAS: 73-78-9 | lidocaine hydrochloride |
CAS: 137-58-6 | Linocaine Base |
CAS: 23239-88-5 | Benzocaine hydrochloride |
CAS:94-09-7 | Benzocaine |
CAS:59-46-1 | Procaine |
CAS: 51-05-8 | Procaine hydrochloride |
CAS: 721-50-6 | Prilocaine |
CAS: 721-50-6 | Prilocaine hydrochloride |
CAS: 5875-6-9 | Proparacaine hydrochloride |
CAS: 637-58-1 | Pramoxine hydrochloride |
CAS: 614-39-1 | Procainamide hydrochloride |
CAS: 98717-15-8 | Ropivacaine hydrochloride |
CAS: 23964-57-0 | Articaine hydrochloride |
Growth Hormne Peptides
T-A001 | MGF | 2mg |
T-A002 | PEG MGF | 2mg |
T-A003 | CJC-1295 with DAC | 2mg |
T-A004 | CJC-1295 without DAC | 2mg |
T-A005 | PT-141 | 10mg |
T-A006 | MT-1(Melanotan-1) | 10mg |
T-A007 | MT-2(Melanotan-2) | 10mg |
T-A008 | GHRP-2 | 5mg |
T-A008 | GHRP-2 | 10mg |
T-A009 | GHRP-6 | 5mg |
T-A009 | GHRP-6 | 10mg |
T-A0010 | Ipamorelin | 2mg |
T-A0011 | Hexarelin | 2mg |
T-A0012 | Sermorelin | 2mg |
T-A0013 | Oxytocin | 1g |
T-A0014 | TB500 | 2mg |
T-A0015 | pentadecapeptide BPC 157 | 2mg |
T-A0016 | Â | 2mg |
T-A0017 | Triptorelin | 2mg |
T-A0018 | Tesamorelin | 2mg |
T-A0020 | Gonadorelin | 2mg |
T-A0020 | Gonadorelin | 10mg |
T-A0021 | DSIP | 2mg |
T-A0022 | Selank | 5mg |
T-A0023 | Epitalon | 10mg |
Peptides |
Specification |
MGF | 2mg |
PEG MGF | 2mg |
CJC-1295 with DAC | 2mg |
CJC-1295 without DAC | 2mg |
PT-141 | 10mg |
MT-1 | 10mg |
MT-2 | 10mg |
GHRP-2 | 5mg |
GHRP-2 | 10mg |
GHRP-6 | 5mg |
GHRP-6 | 10mg |
Ipamorelin | 2mg |
Hexarelin | 2mg |
Sermorelin | 2mg |
Oxytocin | 2mg |
TB500 | 2mg |
Pentadecapeptide BPC 157 | 2mg |
Triptorelin | 2mg |
Tesamorelin | 2mg |
Gonadorelin | 2mg |
Gonadorelin | 10mg |
DSIP | 2mg |
Selank |
5mg  |
1. Quick Detail:
Â
Synonyms: 11-(4-(dimethylamino)phenyl)-17-hydroxy-17-(1-propynyl)-estra-9-dien-3-one;11beta-[4-(n,n-dimethylamino)phenyl]-17alpha-(prop-1-ynyl)-delta4,9-estradiene;17-beta)-(11-bet;17beta)-11-[4-(dimethylamino)-phenyl]-17-hydroxy-17-(1-propynyl)estra-(11bet;17-beta-hydroxy-11-beta-(4-dimethylaminophenyl-1)-17-alpha-(prop-1-ynyl)oest;-17beta-ol-3-one;4,9-dien-3-one;r38486Â
Mifepristone Mifepristone
Mifepristone CAS No.: 84371-65-3
Mifepristone Molecular Formula: C29H35NO2
Mifepristone Molecular Weight: 429.65
Mifepristone Melting Point: 195-198 Degree C
Mifepristone Description: White or almost white or pale yellow crystalline powder
Mifepristone Packing: 1kg/aluminum foil bag
Mifepristone 2. Min. Order quantity: 5g
Mifepristone 3. Payment: Western Union, Moneygram
Mifepristone 4. Shipment: EMS, DHL, FedEx
Mifepristone 5. Delivery: Safe & timely, around 7days after payment.
2. Description:
Mifepristone is a synthetic steroid compound with both antiprogesterone and antiglucocorticoid properties. The compound is a 19-nor steroid with substitutions at positions C11 and C17 (17 beta-hydroxy-11 beta-[4-dimethylamino phenyl] 17 alpha-[1-propynyl]estra-4, 9-dien-3-one), which antagonizes cortisol action competitively at the receptor level.Â
Mifepristone is a progesterone receptor antagonist used as an abortifacient in the first months of pregnancy, and in smaller doses as an emergency contraceptive. It is also a powerful glucocorticoid receptor antagonist,Â
Mifepristone was the first antiprogestin to be developed and it has been evaluated extensively for its use as an abortifacient. The original target for the research group, however, was the discovery and development of compounds with antiglucocorticoid properties. These antiglucocorticoid properties are of great interest in the treatment of severe mood disorders and psychosis, although a review of published articles was inconclusive on their efficacy, and considered the use of these drugs in mood disorders at 'proof of concept' stage. It is on the World Health Organization's List of Essential Medicines.Â
3.Application:
Mifepristone is used alone or in combination with misoprostol (Cytotec) to end an early pregnancy. Early pregnancy means it has been 49 days or less since your last menstrual period began. Mifepristone is in a class of medications called antiprogestational steroids. It works by blocking the activity of progesterone, a substance your body makes to help continue pregnancy.
Mifepristone is also available as another product (Korlym), which is used to control hyperglycemia (high blood sugar) in people with a certain type of Cushing's Syndrome in which the body makes too much of the hormone cortisol. This monograph only gives information about mifepristone (Mifeprex), which is used alone or in combination with another medication to end an early pregnancy. If you are using mifepristone to control hyperglycemia caused by Cushing's syndrome, read the monograph entitled mifepristone (Korlym) that has been written about this product.
Mifepristone COA
Â
Ref. Standard |
According to the CP 2010 version and enterprise internal control standard inspection | ||
Results Of Analysis Tests | |||
Test | Analysis StandardResults |  | |
Description | Light Yellowish Crystalline Powder |  Light Yellowish Crystalline Powder | |
Identification | (1)304nm,260nm. | confirmed | |
Melting Point | 192ºC~196ºC | 192ºC~196ºC | |
Specific Rotation | +124°~ +129° | +127.1° | |
(HPLC) Related substances | (1)(Single):≤0.5% | 0.31% | |
 | (2)(Total):≤1.0% | 0.59% | |
Loss On Drying | ≤0.5% | 0.1% | |
Assay | ≥98.5% | 99.5% | |
Sieve analysis | ≤30¦Ìm | confirmed | |
Conclusion | This product conforms to the CP 2010 and enterprise internal control standards |
Â
Name |
Specification |
MGF | 2mg/vial |
PEG MGF | 2mg/vial |
CJC-1295 with DAC | 2mg/vial |
CJC-1295 without DAC | 2mg/vial |
PT-141 | 10mg/vial |
MT-1(Melanotan) | 10mg/vial |
MT-2 | 10mg/vial |
GHRP-2 | 5mg/vial |
GHRP-2 | 10mg/vial |
GHRP-6 | 5mg/vial |
GHRP-6 | 10mg/vial |
Ipamorelin | 2mg/vial |
Hexarelin | 2mg/vial |
Sermorelin | 2mg/vial |
Oxytocin | 2mg/vial |
TB500 | 2mg/vial |
pentadecapeptide BPC 157 | 2mg/vial |
176-191 | 2mg/vial |
Triptorelin | 2mg/vial |
Tesamorelin | 2mg/vial |
Gonadorelin | 2mg/vial |
Gonadorelin | 10mg/vial |
DSIP | 2mg/vial |
Selank | 5mg/vial |
CAS:94-24-6 | Tetracaine base |
CAS:136-47-0 | Tetracaine hydrochloride |
CAS: 73-78-9 | lidocaine hydrochloride |
CAS: 137-58-6 | Linocaine Base |
CAS: 23239-88-5 | Benzocaine hydrochloride |
CAS:94-09-7 | Benzocaine |
CAS:59-46-1 | Procaine |
CAS: 51-05-8 | Procaine hydrochloride |
CAS: 721-50-6 | Prilocaine |
CAS: 721-50-6 | Prilocaine hydrochloride |
CAS: 5875-6-9 | Proparacaine hydrochloride |
CAS: 637-58-1 | Pramoxine hydrochloride |
CAS: 614-39-1 | Procainamide hydrochloride |
CAS: 98717-15-8 | Ropivacaine hydrochloride |
CAS: 23964-57-0 | Articaine hydrochloride |
Growth Hormne Peptides
T-A001 | MGF | 2mg |
T-A002 | PEG MGF | 2mg |
T-A003 | CJC-1295 with DAC | 2mg |
T-A004 | CJC-1295 without DAC | 2mg |
T-A005 | PT-141 | 10mg |
T-A006 | MT-1(Melanotan-1) | 10mg |
T-A007 | MT-2(Melanotan-2) | 10mg |
T-A008 | GHRP-2 | 5mg |
T-A008 | GHRP-2 | 10mg |
T-A009 | GHRP-6 | 5mg |
T-A009 | GHRP-6 | 10mg |
T-A0010 | Ipamorelin | 2mg |
T-A0011 | Hexarelin | 2mg |
T-A0012 | Sermorelin | 2mg |
T-A0013 | Oxytocin | 1g |
T-A0014 | TB500 | 2mg |
T-A0015 | pentadecapeptide BPC 157 | 2mg |
T-A0016 | Â | 2mg |
T-A0017 | Triptorelin | 2mg |
T-A0018 | Tesamorelin | 2mg |
T-A0020 | Gonadorelin | 2mg |
T-A0020 | Gonadorelin | 10mg |
T-A0021 | DSIP | 2mg |
T-A0022 | Selank | 5mg |
T-A0023 | Epitalon | 10mg |
Peptides |
Specification |
MGF | 2mg |
PEG MGF | 2mg |
CJC-1295 with DAC | 2mg |
CJC-1295 without DAC | 2mg |
PT-141 | 10mg |
MT-1 | 10mg |
MT-2 | 10mg |
GHRP-2 | 5mg |
GHRP-2 | 10mg |
GHRP-6 | 5mg |
GHRP-6 | 10mg |
Ipamorelin | 2mg |
Hexarelin | 2mg |
Sermorelin | 2mg |
Oxytocin | 2mg |
TB500 | 2mg |
Pentadecapeptide BPC 157 | 2mg |
Triptorelin | 2mg |
Tesamorelin | 2mg |
Gonadorelin | 2mg |
Gonadorelin | 10mg |
DSIP | 2mg |
Selank |
5mg  |
Palbociclib is a drug for the treatment of ER-positive and HER2-negative breast cancer developed by Pfizer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6.
It was reviewed and approved under the Food and Drug Administration`s (FDA) accelerated Priority Review and Breakthrough Therapy designation programs on February 3, 2015 as a treatment (in combination with letrozole) for patients with estrogen receptor positive advanced breast cancer.
We produce a series of complete intermediates for Palbociclib, intermediate I (CAS No. 571188-59-5), intermediate II (CAS No. 1013916-37-4) and intermediate III (CAS No. 1016636-76-2) etc.
All of our products are with stable production and strict quality control, making sure your experience with Sunshine Biotech is always enriching, satisfying and fulfilling.
Palbociclib Intermediates,Cas 571188-59-5,Cas 1013916-37-4,Cas 1016636-76-2
Nanjing Sunshine Biotech Co., Ltd , http://www.sunshine-bio.com