Release date: 2013-07-12
LavaAmp, a chain reactor that can be used to copy DNA sequences anytime, anywhere, on the belt. The LavaAmp prototype is made of sheet metal with a small cylindrical protrusion at one end and two thin wires around it. You can use the 5th battery to power it, or connect it directly to the USB port on your laptop. LavaAmp is divided into 3 parts internally. The basic function of this small box doesn't sound very cool: it heats, cools, and then heats up; the liquid can flow in and out, and it looks like nothing changes. Children may mistake it as a toy at first. However, they poke a sway and shake the stuff, and in a short while they may feel boring, then leave it to play. In short, LavaAmp looks unremarkable. However, the lack of attractiveness on the surface is also its extraordinary excellence. Jackson and his team crafted such a machine to confirm the incredible puzzles that bioscientists have solved over the past 3,000 years. LavaAmp is probably the world's smallest chain reactor - the most basic biotech device that can quickly replicate DNA. The chain reactor can regularly raise and lower the temperature inside the machine, allowing the polymerase chain reaction, ie PCR, to proceed. The discovery of this reaction and how to control this reaction was one of the fundamental achievements that could really be applied to industrial scale after the invention of genetic engineering in 1983. The ability of PCR is not just the ability to replicate DNA, it also allows researchers to replicate specific DNA fragments. As long as the biotechnologist knows how to formulate the appropriate reagents, he can synthesize a large number of genes they want to splicing in a short time with a chain reactor. Biotechnological drugs, genetically modified crops, and synthetic biofuels all require PCR reactions, which are the most fundamental part of the manufacturing process. Chain reactors have long been critical to all genetic engineering projects. In the past, a chain reactor had to go to the lab for tens of thousands of dollars. In a way, this is understandable. Although this machine may sound different from advanced electric ceramic pots, PCR requires precise temperature control to react. Even today's chain reactors are routinely used in biological laboratories, and what they do is still incredible. In the billions of years since the formation of DNA in the original slurry, DNA has been constantly replicating at its own pace and using itself as a template. This process is only a moment in the history of the earth. Now, we have machines that can order specific DNA sequences when we want them. Should such a machine cost a lot? After all, there is even one in God's toolbox. Jackson does not think so. LavaAmp is his proud work. LavaAmp expects retail prices to be less than $100. This is to achieve a goal: to allow scientists to manipulate DNA as easily as in a biological laboratory in the San Francisco Bay Area, even in a Congolese village. Or, at least almost as convenient. A basic common spirit of DIY biotechnology is that it is good enough to approximate. Jackson and Nunez Muhica believe that LavaAmp is easy to carry, versatile and inexpensive, and these features will eventually make it an important part of the diagnostic toolbox in developing countries. Unlike the typical toolboxes used today by public health workers, the LavaAmp toolbox is used to detect markers for different diseases without the need to prepare a separate reagent system for each type of bacteria. Instead, a doctor or public medical technician needs only a small set of different primers. The primer is a small piece of genetic code that marks the start and end points of the DNA fragment that needs to be cut and replicated. In the ideal picture of Nunez-Mushika, a medical worker can quickly reach a remote place like Guanarito after the outbreak. He only needs to carry LavaAmp, a DNA reading chip, some tubes with primers for detecting hemorrhagic fever, trypanosomiasis and dengue fever, and then the worker can quickly detect the different pathogens that cause the three diseases. Creatures, and within a few minutes know which pathogen is causing the plague outbreak. The raw materials used for testing are cheap, the tools are easy to carry, and the technology is efficient. Governments in developing countries are fully able to afford bulk purchases of such tool boxes. Entrepreneurs do not have to rely on millions of dollars in venture capital support to produce and sell LavaAmp tool boxes. It is important to know that a large amount of venture capital injection requires the company to make tens of millions of dollars a year to make the investment return. This is especially important when you are producing a product that targets the world's poorest people. Another key part of the toolbox is the small electronic chip that reads the information in the DNA samples processed by LavaAmp. Such devices have not yet been developed, but the steady development of sequencing technology makes it seem likely that such devices will be developed. All of the above parts will be small enough to be caught on the belt. This is a method of extensive use of biotechnology, which is the main reason why people are skeptical about the biology outside the system. If you are in your own garage, decorating a Honda Civic with the style of "Speed ​​and Passion", but this car can't start, then you can pick up a socket wrench and screw it up until the car starts. In the process, your car will not drive to the west, at least not as dead as the creature died. You just finished a huge iPhone app, but what if it keeps sending your credit card number to all your Weibo fans? You must be filling the loopholes without sleep. You won't delete all the code, you can't solve this problem in a hundred ways. Real deaths only occur in biological projects. Therefore, in general, strict management of experimental equipment is considered a very important prerequisite for the work of biological laboratories. In the ideal laboratory, bright white light sprinkled on the black test bench. In fact, such a perfect laboratory exists only in the setting of Hollywood movies, as well as in the public relations manual of the top research universities in the country. In developing countries, power and tap water are not guaranteed, and aseptic conditions are often only a luxury that can be seen from a distance, especially when working in the field. But LavaAmp developers believe that their devices can do their best.
Source: Pacific Internet
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