According to EurekAlert!, the AAAS global science news service platform, personalized cancer vaccines that cultivate the immune system to attack tumors have yielded encouraging results in patients with ovarian cancer.
Current cancer vaccines have shown good prospects in clinical trials, but they are still rarely used in routine clinical practice worldwide. Many vaccine designs are designed to recognize specific molecules that are often present in cancer cells by culturing immune cells, but this may fail because of the different tumors that different people have.
To solve this problem, Lana Candelafort from the University of Lausanne in Switzerland led the team to develop a personalized vaccine for each tumor. To do this, samples need to be extracted from female tumors and acid is used to kill the cells, exposing specific molecules that are usually hidden. These dead cells are then mixed with the immune cells in the female blood, grown in the laboratory for a few days, and then injected into the patient.
To test the safety of this method, the researchers provided personalized vaccines to five women with recurrent ovarian cancer, provided personalized vaccines to 20 other women with ovarian cancer, and shared it with one or two chemotherapy drugs. These chemotherapeutic drugs are also thought to enhance the immune system while killing cancer cells.
The tester was given a dose of the vaccine every three weeks for 15 weeks and then injected once a month until the development of the disease was completed or the vaccine was supplied. The team found that the personalized vaccine was safe and did cause an immune response to the tumor. Women who showed a stronger immune response lived longer than those who performed a weaker immune response. Patients who used both the vaccine and the two chemotherapeutic drugs showed the best survival rate - 80% of these women survived after two years.
The results of the study also show that it is very important to keep female tumor samples at the time of surgery, which will help develop personalized vaccines. (Reporter Fang Linlin)
Editor's Editor
The same disease often shows different symptoms in different patients. The same treatment method may also have significant differences in results obtained for different patients. The underlying reason is that the level of immunity between individuals is different. The use of personalized diagnosis and treatment methods to accurately treat patients represents another major advancement in modern medicine. However, the implementation of this treatment method depends not only on the level of medical technology, but also on the affordability of a social medical resource.
Frozen PUD raw material
Pud Raw Material,Frozen Pud Raw Material,Frozen Raw Vannamei Shrimp,Fresh Raw Material Vannamei Shrimp
Zhoushan Junwei Aquatic Products Co., Ltd. , https://www.junweiaquatic-intl.com