The study found that 70-day-old pig fetuses, 41-day-old sheep fetuses, 50-day-old bovine fetuses, and 14-day-old chicken embryos have established immunoreactivity against viral infections, although reported in 14-16 days. Inoculation of chicken embryos with Newcastle disease virus and turkey herpes virus vaccine can provide immune protection to chicks, but the fetus has a lower anti-infective capacity than adult animals. Therefore, certain vaccines that can be safely used in adult animals are banned from pregnant animals, such as bluetongue vaccines and bovine infectious laryngotracheitis vaccines, which are safe for adult cattle but can cause severe fetal disease and death. In addition, the antibodies obtained by the larvae after breastfeeding can interfere with the vaccination effect. When the maternal antibody is not obtained before lactation, the newborn babies are vaccinated, which may avoid the interference of maternal antibodies. This is called pre-immune immunity. There have been reports of better results in the prevention of immune in piglets.
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