Alcohol and smoking have an important impact on esophageal cancer
January 18, 2019 Source: Science and Technology Daily Author: Zhang Meng Ran
Window._bd_share_config={ "common":{ "bdSnsKey":{ },"bdText":"","bdMini":"2","bdMiniList":false,"bdPic":"","bdStyle":" 0","bdSize":"16"},"share":{ }};with(document)0[(getElementsByTagName('head')[0]||body).appendChild(createElement('script')) .src='http://bdimg.share.baidu.com/static/api/js/share.js?v=89860593.js?cdnversion='+~(-new Date()/36e5)];According to a recent paper published online by the British journal Nature, cancer mutations occur in esophageal cells with normal physiological characteristics and accumulate over time, and risk factors, including alcohol and smoking, promote mutant cells. increase the amount. This confirms the important impact of these environmental factors on the development of esophageal cancer.
Esophageal squamous cell carcinoma (ESCC) is the most common type of esophageal cancer in the Asian population. Usually, patients will have a series of symptoms such as dysphagia and sudden weight loss, which will bring great pain to patients. Recent studies have shown that precancerous clonal cells appear in physiologically normal tissues, but the relationship between these cells and established risk factors for esophageal squamous cell carcinoma (such as age, alcohol consumption, and smoking) is unclear.
This time, the Kyoto University research team tested esophageal tissue samples from 139 patients (diagnosed as esophageal squamous cell carcinoma or no cancer) to investigate cell mutations. At the same time, the patient's history of drinking and smoking was also recorded. According to the team report, many samples contain cloned cells that have been mutated, especially the cancer-associated gene NOTCH1, and such cells may appear as early as infancy. The number of mutant cells in the esophagus increases with the age of the random body. In older patients (at least 70 years old), the mutant cells account for a considerable proportion of esophageal epithelial cells.
Despite this observation, the researchers report that many of these cells do not develop into cancer, and the lifetime risk of esophageal squamous cell carcinoma remains low. The authors also point out that heavy drinking and smoking appear to accelerate the accumulation of mutations, which means that these environmental factors have a more critical impact on the risk of esophageal squamous cell carcinoma.
Small Molecule Peptides Powder
Small molecule peptides powder:Bovine bone oligopeptide powder,Fish collagen peptide powder,Sunflower disk oligopeptide powder,Oat protein peptide powder,Corn oligopeptide powder,Soybean peptide powder,Whey protein peptide.
Small Molecule Peptides Powder,Collagen Peptide Powder,Small Molecule Oligopeptide Powder,Marine Collagen Peptides Protein Powder
Shaanxi Zhongyi Kangjian Biotechnology Co.,Ltd , https://www.zhongyibiology.com